Pyridines and derivatives
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Filtered Search Results
Alkali Scientific Peptone, 1 Gram Capsules, 1 Kg
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Peptone, available in 1g capsules (1kg total per bottle), is a high-quality protein source commonly used in microbiological and biochemical media. This product provides essential amino acids, peptides, and growth factors required for the cultivation of a wide range of microorganisms. The 1-gram capsules allow for precise and convenient measurement of peptone, ensuring consistent media preparation without the need for bulky containers. It is widely used in media for bacterial growth, fermentation studies, and microbiological quality control. This product is ideal for enhancing the nutritional content of culture media for both research and industrial microbiological applications.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Cortistatin-14 | 186901-48-4 | 99.98% | 1720.03 | 1 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cortistatin-14 is a neuropeptide structurally and functionally similar to somatostatin. It binds to somatostatin receptors (sst1-sst5) and exhibits anticonvulsant, neuroprotective, and anti-inflammatory properties.
- Binds to somatostatin receptors (sst1-sst5)
- Exhibits anticonvulsant effects
- Provides neuroprotective effects
- Possesses anti-inflammatory properties
- Reduces release of calcitonin gene-related peptide from peripheral sensory nerve endings
- Decreases secretion of cytokine IL-1β in mouse peritoneal macrophages
- Reduces acute neurogenic plasma protein leakage
- Inhibits mechanical hyperalgesia
- Regulates pituitary secretion
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Butylated hydroxytoluene-d21 | 64502-99-4 | 98.7% | 241.48 | 25 MG
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Butylated hydroxytoluene-d21 is a deuterium-labeled version of Butylated hydroxytoluene, functioning as an antioxidant commonly found in food and food-related products. It also acts as a Ferroptosis inhibitor. Stable heavy isotopes, such as deuterium, are incorporated into drug molecules as tracers for quantitative analysis during drug development, potentially influencing pharmacokinetic and metabolic profiles.
- Can be utilized as a tracer
- Suitable for use as an internal standard in quantitative analysis methods such as NMR, GC-MS, or LC-MS
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000663996 RUCAPARIB 10MM/1ML
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Medchemexpress LLC N-Acetylputrescine hydrochloride | 18233-70-0 | 99.0% | 166.65 | 25 MG
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N-Acetylputrescine hydrochloride is a polyamine metabolite that regulates cell proliferation and signal transduction by participating in polyamine acetylation modification. It may reduce the positive charge of polyamines, affect protein-nucleic acid interactions, and promote cell growth. Its concentration changes can assist in disease diagnosis and microbial cell wall structure research.
- Regulates cell proliferation and signal transduction
- Participates in polyamine acetylation modification
- May reduce the positive charge of polyamines
- Affects protein-nucleic acid interactions
- Promotes cell growth
- Potential biomarker for lung cancer progression
- Potential biomarker for Parkinson's disease
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Medchemexpress LLC Denifanstat | 1399177-37-7 | 99.6% | 439.55 | 25 MG
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Denifanstat (TVB-2640) is an orally active, potent Fatty Acid Synthase (FASN) inhibitor (IC50 of 0.052 μM, EC50 of 0.072 μM) with potential for fatty liver disease and cancer research. Also known as FASN-IN-2 and ASC-40, it has a molecular weight of 439.55 and formula C27H29N5O. This white to off-white solid is for research use only.
- Orally active and potent fatty acid synthase (FASN) inhibitor.
- IC50 of 0.052 μM and EC50 of 0.072 μM for FASN inhibition.
- Potential for fatty liver disease and cancer research.
- Prevents palmitoylation of SARS-CoV2 spike protein.
- Suppresses SARS-CoV-2 virus replication, reduces weight loss, and prolongs survival after SARS-CoV-2 infection.
- Used in published research for cancer and SARS-CoV-2 studies.
- Undergoing clinical trials for MASH/NASH, acne vulgaris, and various cancers.
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Medchemexpress LLC POL1-IN-1 | 1822358-25-7 | 98.1% | 356.42 | 25 MG
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POL1-IN-1 is an RNA polymerase 1 (POL1) inhibitor with an IC₅₀ of less than 0.5 μM. It inhibits ribosome biogenesis by preventing POL1 transcription.
- RNA polymerase 1 (POL1) inhibitor
- Inhibits ribosome biogenesis
- Used for research purposes
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Medchemexpress LLC BIO8898 | 98.8% | 909.13 | 25 MG
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BIO8898 is a potent inhibitor of CD40-CD154. It inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 μM and also inhibits CD40L-induced apoptosis.
- Potent CD40-CD154 inhibitor.
- Inhibits soluble CD40L binding to CD40-Ig.
- Inhibits CD40L-induced apoptosis.
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Selleck Chemical LLC HPK1-IN-2
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HPK1-IN-2 is a potent and orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1 a serine/threonine Ste20-related protein kinase) Lck and Flt3 with IC50 of 0 05 M IC50 of 0 5 M and IC50 of 0 05 M respectively HPK1-IN-2 exhibits antitumor activity
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Selleck Chemical LLC Molibresib
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Molibresib (I-BET-762 GSK525762 GSK525762A) is an inhibitor for BET proteins with IC50 of 35 nM in a cell-free assay suppresses the production of proinflammatory proteins by macrophages and blocks acute inflammation highly selective over other bromodomain-containing proteins
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Selleck Chemical LLC Vesatolimod
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Vesatolimod (GS-9620) is a potent and selective orally active small molecule agonist of Toll-like receptor 7
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Medchemexpress LLC 1-Adamantaneethanol | 6240-11-5 | 99.8% | 180.29 | 1 G
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1-Adamantaneethanol is a hapten that influences peptide binding by MHC II. It is for research use only and not sold to patients.
- Influences peptide binding by MHC II.
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Medchemexpress LLC Dnl343 | 2278265-85-1 | 99.9% | 457.83 | 25 MG
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DNL343 is a potent, selective, orally active, and brain-penetrant activator of eukaryotic initiation factor eIF2B. It inhibits the integrated stress response (ISR) in the central nervous system (CNS), reversing neurodegeneration and neuroinflammation. It also prevents motor dysfunction and premature death in eIF2B loss-of-function (LOF) mutant mice, making it a candidate for studying neurodegenerative diseases.
- Potent, selective, orally active, and brain-penetrant activator of eukaryotic initiation factor eIF2B.
- Inhibits integrated stress response (ISR) activity in the central nervous system (CNS).
- Reverses neurodegeneration and neuroinflammation.
- Prevents motor dysfunction and premature death in eIF2B loss-of-function (LOF) mutant mice.
- Potential for use in neurodegenerative disease studies.
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Medchemexpress LLC 2-Bromo-5-nitropyridine | 4487-59-6 | 203.00 | 10 G
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2-Bromo-5-nitropyridine is a biochemical reagent used as a biological material or organic compound for life science related research.
- Used as a biological material for research
- Used as an organic compound for research
- Suitable for life science research applications
- Soluble in DMSO at 100 mg/mL (ultrasonic)
- Functions as a biochemical assay reagent
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Medchemexpress LLC TH34 | 2196203-96-8 | 99.5% | 256.30 | 1 ML
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TH34 is an inhibitor of HDAC6, HDAC8, and HDAC10, with IC50 values of 4.6 μM, 1.9 μM, and 7.7 μM, respectively. It exhibits high selectivity over HDAC1, HDAC2, and HDAC3. For research use only, not intended for patients. TH34 induces caspase-dependent programmed cell death and cell cycle arrest in neuroblastoma cells.
- HDAC6/8/10 inhibitor
- IC50s: 4.6 μM (HDAC6), 1.9 μM (HDAC8), 7.7 μM (HDAC10)
- High selectivity over HDAC1/2/3
- Induces caspase-dependent programmed cell death in neuroblastoma cells
- Induces cell cycle arrest in neuroblastoma cells
- Appearance: solid
- Color: white to off-white
- For research use only
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